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long-term safety data is absent

& Stenvinkel, P

The presence of human CD31 (human-specific antibody) vascular structures that appear to have anastomosed into the mouse kidney parenchyma further supports the presence of vascularization within our organoids and ongoing de novo vascularization

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Inhibition of c-Met with PF2341066 and siRNA decreases EGF-induced phenotypes of invasion by 86% and motility by 81%, suggesting that a novel form of c-Met activation is utilized by EGFR to maximize these biological effects